Cloud and AI strategy, from architecture to the boardroom.

I lead life sciences technology for AWS in US East. Nineteen years, $300M+ influenced, and 24 publications.

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Sudhanshu Malhotra
Boston, Massachusetts

About

Transformational cloud technology leader with 19+ years driving enterprise digital transformation, GenAI adoption, and large-scale cloud architecture across regulated industries. AWS-certified architect who pairs broad enterprise experience with deep domain expertise in life sciences, accelerating drug discovery, genomics, and diagnostic workflows while delivering measurable business impact.

Proven track record influencing $300M+ in revenue while reducing operational costs by 50%+ through strategic cloud architecture and adoption strategies. Recognized thought leader with 24 published technical articles and presentations reaching 100K+ industry professionals across cloud architecture, GenAI, and enterprise-scale migrations.

Currently partnering with enterprises to design and build production agentic platforms, guiding teams through multi-agent orchestration, RAG pipelines, LLM evaluation, and integrating GenAI into existing technology stacks.

Master of Science in Electrical Engineering with comprehensive AWS certifications including Solutions Architect Professional, DevOps Engineer Professional, and Machine Learning Specialty.

Cover of GenAI: A Builder's Guide

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GenAI: A Builder's Guide

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A guide for builders and architects implementing production Generative AI. Proven patterns, hard-won practices, and strategies for deploying GenAI at scale.

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Experience

Five roles, one arc: from storage integration to the architecture of production GenAI.

2022 to present

Principal Solutions Architect, HCLS Tech Lead

Amazon Web Services, Boston

  • Lead life sciences technology for AWS US East, influencing $300M+ in revenue at 20%+ year over year growth.
  • Advise C-level executives at Fortune 500 life sciences companies on cloud and AI strategy.
  • Set technical direction for enterprise drug discovery, genomics, and diagnostic platforms.
  • Guide enterprise teams building production agentic platforms: multi-agent orchestration, RAG, and LLM evaluation.
  • Author technical content reaching 100K+ professionals, shaping cloud adoption across the sector.
2018 to 2022

Senior Solutions Architect, Sales

Amazon Web Services, Boston

  • Influenced $25M+ in revenue through enterprise cloud transformation initiatives.
  • Delivered 100%+ year over year territory revenue growth for three consecutive years.
  • Led 50+ workshops, deep dives, and executive briefings for enterprise accounts.
  • Built long-term executive relationships positioning AWS as a strategic transformation partner.
2015 to 2018

Cloud Consultant, Professional Services

Amazon Web Services, Boston

  • Led technical engagements with IT executives to accelerate enterprise cloud adoption.
  • Owned solution architecture for scale, resiliency, security, and maintainability.
  • Coached customer teams to self-sufficiency, building lasting internal cloud competency.
2012 to 2015

Member of Technical Staff, DevOps

NetApp, Waltham

  • Founding engineering team member for ONTAP Cloud, now Cloud Volumes ONTAP.
  • Led end-to-end automation across AWS and Azure for a new product line.
  • Delivered $1M+ in annual savings through resource optimization.
2007 to 2012

Senior Systems Integration Engineer

EMC Corporation, Hopkinton

  • Defined test strategy for enterprise storage systems and virtualization platforms.
  • Architected validation environments spanning storage, SAN fabrics, and disaster recovery.

Core competencies

Executive advisory
C-level engagement, strategic planning, digital transformation, executive briefings
Technology leadership
Technical direction, cross-functional leadership, stakeholder management, mentoring
Cloud strategy and architecture
Enterprise solutions design, AWS Well-Architected Framework, multi-cloud strategy
GenAI and machine learning
Agentic architectures, multi-agent orchestration, RAG pipelines, LLM evaluation
Life sciences technology
Drug discovery, genomics workflows, clinical trial optimization, regulatory compliance
Business impact and FinOps
Revenue growth, cost optimization, resource management, operational excellence
Thought leadership
Publishing, public speaking, technical writing, community building
Platform and delivery
Infrastructure-as-Code, CI/CD, container orchestration, automation at scale

Publications and thought leadership

Twenty four technical articles, case studies, and books, read by more than 100,000 industry professionals.

AWS certifications

  • Solutions Architect, Professional
  • DevOps Engineer, Professional
  • Machine Learning, Specialty
  • AI Practitioner
  • Solutions Architect, Associate
  • SysOps Administrator, Associate
  • Developer, Associate
  • Cloud Practitioner

Key achievements

$300M+ Revenue influenced in life sciences cloud adoption
50%+ Cost reduction delivered for enterprise customers
100K+ Views on technical content and presentations
24 Published technical articles and books
100%+ Year over year growth, three consecutive years
$1M+ Infrastructure savings through automation

Get in touch

Always open to discussing cloud architecture, GenAI and agentic systems, or strategic partnerships.

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